ABSTRACT
[Objective] Summarize the treatment of type 2 diabetes from Prof. SUN Zhi 's experience in order to direct clinical learning, by using acupuncture therapy to purge stomach fire and reinforce the spleen. [Method] Sum up the Prof. SUN Zhi 's academic ideas and clinical experience on how to select acupoints by learning from professors and researching some typical cases. [Result] Prof. SUN Zhi takes advantage of the main pathogenesis from type 2 diabetes to help guide acupoints selection on the treatment of stomach preponderance and spleen weakness. The main acupoints are Zusanli, Neiting, Zhongwan, Sanyinjiao, Taibai and Piyu. Stomach meridian requires lifting, thrusting, twirling and rotating on Zusanli, Zhongwan and Neiting, while Spleen Maridian requires lifting, thrusting, twirling and rotating on Sanyinjiao, Taibai and Piyu, which in together benefit purging fu-organs to eliminate heat, strengthening spleen and nourishing qi and improving islet function.[Conclusion] Professor SUN Zhi has a unique experience especially in terms of diabetes treatment with the theory of spleen and stomach, in which the clinical efficacy has been significantly achieved. His performance has important direction to our future research and study.
ABSTRACT
[Objective] Summarize the treatment of type 2 diabetes from Prof. SUN Zhi 's experience in order to direct clinical learning, by using acupuncture therapy to purge stomach fire and reinforce the spleen. [Method] Sum up the Prof. SUN Zhi 's academic ideas and clinical experience on how to select acupoints by learning from professors and researching some typical cases. [Result] Prof. SUN Zhi takes advantage of the main pathogenesis from type 2 diabetes to help guide acupoints selection on the treatment of stomach preponderance and spleen weakness. The main acupoints are Zusanli, Neiting, Zhongwan, Sanyinjiao, Taibai and Piyu. Stomach meridian requires lifting, thrusting, twirling and rotating on Zusanli, Zhongwan and Neiting, while Spleen Maridian requires lifting, thrusting, twirling and rotating on Sanyinjiao, Taibai and Piyu, which in together benefit purging fu-organs to eliminate heat, strengthening spleen and nourishing qi and improving islet function.[Conclusion] Professor SUN Zhi has a unique experience especially in terms of diabetes treatment with the theory of spleen and stomach, in which the clinical efficacy has been significantly achieved. His performance has important direction to our future research and study.
ABSTRACT
OBJECTIVE:To investigate clinical efficacy and adverse reactions(ADRs)of 4 kinds of the second-generation anti-psychotic drugs in the treatment of acute phase of schizophrenia. METHODS:159 patients with schizophrenia were randomly divid-ed into risperidone group(40 cases),olanzapine group(40 cases),aripiprazole group(39 cases)and ziprasidone group(40 cas-es). All groups were given routine dosage of relevant medicine by routine usage for 6 weeks. Mental status of patients were mea-sured by PANSS before treatment and after 2,4 and 6 weeks of treatment. At the same time,blood glucose,blood lipid,prolac-tion and other metabolic and biological indicators were all detected. RSESE,BARS and UKU were adopted to evaluate ADR. RE-SULTS:A total of 100 patients completed the study. Compared with aripiprazole group and ziprasidone group,risperidone and olan-zapine inhibited symptom more rapidly,with statistical significance (P<0.05). After treatment,body mass index and abdominal circumference of olanzapine group were significantly higher than those of other 3 groups,with statistical significance (P<0.05). Low density lipoprotein of olanzapine group was increased significantly,there was statistical significance compared to ziprasidone group and aripiprazole group(P<0.05). Prolactin level of risperidone group was significantly higher than those of other 3 groups, while that of aripiprazole group was significantly lower than those of other 3 groups,with statistical significance(P<0.05). ADRs of 4 drugs were mild or moderate,most of whom could be alleviated by symptomatic treatment. CONCLUSIONS:In the treatment of acute phase schizophrenia,4 drugs of the second-generation have similar curative effect in symptoms control,among which ris-peridone and olanzapine inhibit positive symptom more rapidly while more ADRs that related to lipid and glucose metabolism and prolactin also show. Aripiprazole and ziprasidone induce less ADRs relatively,and patients show better tolerability. Physicians should consider all kinds of factors in drugs selection,and make individualized treatment plan.
ABSTRACT
OBJECTIVE: To survey the habits of public drug use in China and its reasons and to put forward countermeasures so as to provide reference for government and decision-making department. METHODS: From Nov. 2008 to Feb. 2009, questionnaire survey was adopted in 31 provincial administrative regions except for Hong Kong, Macao and Taiwan. 26 000 questionnaires were collected and 1 100 physicians were interviewed. SPSS17.0 software was used to analyze 11 796 valid questionnaires statistically. The frequency of words used by physicians was counted. RESULTS: The residents don’t have enough knowledge to support them to use medicine rationally. And they are not compliant with prescription but take medicine by arbitrariness. 44.88% of residents don’t buy medicines according to prescriptions and 74.39% don’t take medicine following treatment course, stop taking medicine once symptom relieve or change the category of drugs frequently. CONCLUSION: The improvement of pharmaceutical market environment, enhancement of medication guide and popularization of medication knowledge can promote rational use of drug.